CBN vs CBD: The Ultimate Guide to Their Health Benefits and Uses

Published: 7/1/2025
By:
Mountains

Gone are the days when cannabis was limited to just two cannabinoids: THC and CBD. Now, a range of minor cannabinoids like CBN, CBG, and CBC are gaining popularity in the wellness space. 

Despite sharing similarities in their abbreviated names and origin, CBD (cannabidiol) and CBN (cannabinol) have both unique effects and characteristics that set them apart. CBD has earned its reputation for its ability to treat anxiety, stress, and sleep disorders, among others. CBN is often marketed as a sleep aid and is gaining popularity to support sleep quality. 

In this CBN vs. CBD guide, we’ll compare these two cannabinoids and explore their potential health benefits and uses.

Understanding CBN and CBD

What is CBD?

CBD is the primary cannabinoid present in the cannabis sativa plant and is noted for its non-psychoactive effects. That means it doesn’t produce the high which is typically associated with THC. Its non-psychoactive properties make it a popular choice for those seeking relief without any mind-altering effects. 

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What is CBN?

CBN is a minor cannabinoid that forms after the degradation of THC over time when the plant is exposed to more oxygen. Unlike CBD, which is found in abundance in cannabis plants, CBN is present in trace amounts in the plant. 

Though considered non-psychoactive, it has a mild psychoactive effect— though less intense compared to THC—and is often associated with sedative effects, earning it a reputation as a natural sleep aid.

If you want to know the benefits of CBD and THC gummiesread our blog to learn how they may help improve sleep quality, manage pain, and reduce anxiety!

CBN vs. CBD: Differences between CBN and CBD

Derivation:

CBD: CBD is an active ingredient in cannabis plants that comes from CBDa after the process of decarboxylation by heating cannabis. CBD is found in both hemp and cannabis plants. 

CBN: CBN or Cannabinol comes from THC when its molecules break down with the exposure of oxygen when the hemp material matures.  Chemical alteration is required to produce CBN from plant material.

Effects:

CBD:

CBD is a well-researched cannabinoid and may lessen feelings of anxiety and promote an overall sense of calm. Plus, evidence also shows that it may also help balance the intoxicating effects that THC produces. 

CBN: 

As the oxidation and excessive amount of heat and light turn THC molecules into CBN, it may have mild psychoactive effects. However, it won’t get you high like THC.

Curious to know the difference between THC vs. THCv, check out our complete guide on their key differences.

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How they interact with the body: 

CBD:

CBD and CBN both interact with the body’s endocannabinoid system (ECS) but in different ways. ECS is composed of receptors and chemical messengers that control various functions, from mood regulation to emotional processing. CBD shows low affinity to CB1 and CB2 receptors. CBD interacts with the ECS by binding to CB2 cannabinoid receptors, resulting in transmitting signals that affect the cell, tissue, or organ associated with that receptor. 

CBN

Unlike CBD, CBN acts on the endocannabinoid system’s cannabinoid receptors differently. It binds directly to CB1 and CB2 receptors but less effectively than THC and impacts various cannabinoid and non-cannabinoid receptors. These interactions may influence various physiological processes, including immune response, mood regulation, neuroprotection, and inflammation.

Health benefits  of CBD and CBN

CBD

  • Support sleep: CBD promotes relaxation and may help improve sleep quality.

  • Pain management: CBD is anti-inflammatory and appears to be effective in relieving chronic pain. 

  • Reduce anxiety and stress: CBD has been proven to treat anxiety with or without insomnia. 

CBN

  • Neuroprotective properties: CBN may offer neuroprotective benefits to support focus and mental clarity

  • Sleep aid: CBN is touted as a ‘sleep cannabinoid’ and is being studied for its potential benefits for sleep disorders. 

  • Support post-workout recovery: CBN may enhance the effects of THC and may support THC in promoting post-workout recovery.

Uses of CBD and CBN

CBD

CBD is one of the major cannabinoids that has been extensively studied for its potential therapeutic benefits. It is analgesic, anxiolytic, and anti-inflammatory, meaning it can be used to relieve pain, reduce anxiety, and decrease inflammation in the body. 

It is also studied for its effects on sleep. Studies have shown that CBD may help improve sleep quality in individuals experiencing sleep disturbances. When combined with CBN, CBD may promote relaxation and improve overall sleep quality in individuals who tend to stay asleep throughout the night and experience physical restlessness.

CBN

As a byproduct of THC degradation, CBN is known to have sedative effects. Research on CBN is still in its infancy, but it is being studied for sleep disorders, and more research is emerging about the potential use of this compound. 

When combined with other cannabinoids, its efficacy in improving sleep has been reported. While more research is needed to fully evaluate its effects, it may help reduce the ease with which sleep is disturbed.

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Do you want to sleep better or calm your racing thoughts? Whether you struggle with restless nights or want to restore calm, we offer cannabinoid-rich products that target issues like muscle tension and stress, and potentially aid in sleep and overall tranquility. Shop now at Smokeland to find the cannabinoid-rich product for your needs with fast, reliable weed delivery in Oakland, weed delivery in San Jose, and weed delivery in Sacramento!